che2mca medicinal chemistry a
MEDICINAL CHEMISTRY A
CHE2MCA
2019
Credit points: 15
Subject outline
Students will be introduced to the chemical principles that are required to understand the action and behaviours of a drug compound. The main areas of study include an introduction to the chemistry and nomenclature of carbohydrates, lipids, steroids and heterocyclic compounds and some of their reactions. This unit will provide an understanding of how the chemical structure and behaviour of drug molecules relate to the activity of drugs in biological systems, and how this knowledge can be used to devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR), drug-receptor interactions and drugs metabolism. This unit will also contain a computer based practical component.
SchoolSchool of Molecular Sciences/LIMS
Credit points15
Subject Co-ordinatorJasim Al-Rawi
Available to Study Abroad StudentsYes
Subject year levelYear Level 2 - UG
Exchange StudentsYes
Subject particulars
Subject rules
Prerequisites (CHE1C1A and CHE1C1B) or (CHE1CHF and CHE1APL)
Co-requisitesN/A
Incompatible subjectsN/A
Equivalent subjectsN/A
Special conditionsN/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | An Introduction to Medicinal Chemistry | Prescribed | Patrick, G., 2013 (5th edition) | Oxford University Press |
| Readings | Medicinal Chemistry: An Introduction | Recommended | Thomas, G., 2007 (2nd edition) | Wiley |
| Readings | Lecture semi-notes and practical are lodged on the LMS | Prescribed | La Trobe University | La Trobe University |
| Readings | Organic chemistry | Prescribed | Bruice, P. Y., 2017 (8th edition) | Pearson |
Graduate capabilities & intended learning outcomes
01. Apply understanding of the chemistry of important biological molecules such as carbohydrates, lipids, steroids and heterocyclic molecules to medicinal products.
- Activities:
- Taught in lectures, tutorials, practical workshops, practice problems from text. Assessed in tests and exam.
02. Apply advanced understanding of the chemistry of organic compounds and its impact on syntheses to enhance drug efficacy.
- Activities:
- Taught in lectures, tutorials, practical workshops, practice problems from text and online. Assessed in tests, exam and practical workshop reports.
03. Use the major concepts and language of pharmaceutical and medicinal chemistry correctly.
- Activities:
- Taught in lectures, tutorials, practical workshops, practice problems from text and online. Assessed in tests, exams and practical workshop reports.
04. Determine likely routes of administration through recognition of drug structures, identification and prediction of likely metabolic and elimination pathways, solubility and metabolism.
- Activities:
- Taught in lectures, tutorials, practical workshops, practice problems from text and online. Assessed in tests, exams and practical workshop reports
05. Devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR).
- Activities:
- Taught in lectures, tutorials, practical workshops, practice problems from text and online. Assessed in tests, exam and practical workshop reports.
Subject options
Select to view your study options…
Albury-Wodonga, 2019, Semester 1, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorKeith White
Class requirements
PracticalWeek: 15 - 15
One 3.0 hours practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.
TutorialWeek: 11 - 22
One 1.0 hours tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.
LectureWeek: 10 - 22
Three 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Computer LaboratoryWeek: 13 - 16
One 3.0 hours computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
"Computer Laboratory simulation"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| One 3-hour end-of-semester written examination (3,000-words equivalent) | 60 | 01, 02, 03, 04, 05 | |
| Two in-class tests (15% each) (600-words equivalent in total) | 30 | 01, 02, 03 | |
| Two laboratory reports (5% each) (300-words equivalent in total) | 10 | 02, 03 |
Bendigo, 2019, Semester 1, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJasim Al-Rawi
Class requirements
PracticalWeek: 15 - 15
One 3.0 hours practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.
TutorialWeek: 11 - 22
One 1.0 hours tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.
LectureWeek: 10 - 22
Three 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Computer LaboratoryWeek: 13 - 16
One 3.0 hours computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
"Computer Laboratory simulation"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| One 3-hour end-of-semester written examination (3,000-words equivalent) | 60 | 01, 02, 03, 04, 05 | |
| Two in-class tests (15% each) (600-words equivalent in total) | 30 | 01, 02, 03 | |
| Two laboratory reports (5% each) (300-words equivalent in total) | 10 | 02, 03 |
Singapore (PSB), 2019, Term L3, Night
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
TutorialWeek: 19 - 23
One 12.0 hours tutorial per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
"12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online."
LectureWeek: 19 - 23
One 36.0 hours lecture per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."
Computer LaboratoryWeek: 19 - 23
One 3.0 hours computer laboratory per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
PracticalWeek: 19 - 23
One 3.0 hours practical per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| One 3-hour end-of-semester written examination (3,000-words equivalent) | 60 | 01, 02, 03, 04, 05 | |
| Two in-class tests (15% each) (600-words equivalent in total) | 30 | 01, 02, 03 | |
| Two laboratory reports (5% each) (300-words equivalent in total) | 10 | 02, 03 |
Singapore (PSB), 2019, Term L3, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
TutorialWeek: 19 - 23
One 12.0 hours tutorial per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
"12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online."
LectureWeek: 19 - 23
One 36.0 hours lecture per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."
Computer LaboratoryWeek: 19 - 23
One 3.0 hours computer laboratory per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
PracticalWeek: 19 - 23
One 3.0 hours practical per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| One 3-hour end-of-semester written examination (3,000-words equivalent) | 60 | 01, 02, 03, 04, 05 | |
| Two in-class tests (15% each) (600-words equivalent in total) | 30 | 01, 02, 03 | |
| Two laboratory reports (5% each) (300-words equivalent in total) | 10 | 02, 03 |