pha1pfa pharm formulation a
PHARMACEUTICAL FORMULATION A
PHA1PFA
2017
Credit points: 15
Subject outline
This subject introduces students to the pharmaceutical sciences and covers the areas of physical chemistry and laboratory skills necessary to prepare and understand the formulation of pharmaceutical products. This subject focuses on solution formulations. Students will be introduced to products and routes of administration, absorption, distribution and elimination of drugs. They will study pharmaceutically relevant physicochemical phenomena, formulation of solutions, and pharmaceutical calculations.
SchoolSchool of Molecular Sciences/LIMS
Credit points15
Subject Co-ordinatorDavid Morton
Available to Study Abroad StudentsNo
Subject year levelYear Level 1 - UG
Exchange StudentsNo
Subject particulars
Subject rules
Prerequisites Students enrolled in SHPB, SBPB or SVPB must complete CHE1C1A and PHA1IPP. Students enrolled in SBMSSI and SBSSI must complete CHE1CIA
Co-requisitesN/A
Incompatible subjectsN/A
Equivalent subjectsN/A
Special conditionsN/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | Aulton's Pharmaceutics The Design and Manufacture of Medicines | Prescribed | Aulton, ME and Taylor, K. 2013 | 4TH ED., LONDON: CHURCHILL LIVINGSTONE |
| Readings | Australian Pharmaceutical Formulary and Handbook | Prescribed | Pharmaceutical Society of Australia | 23RD ED, CANBERRA: PHARMACEUTICAL SOCIETY OF AUSTRALIA, 2012 |
| Readings | Pharmaceutical Formulations - Solutions. Practical Laboratory Manual | Prescribed | La Trobe University | La Trobe University |
| Readings | Pharmaceutical Practice | Prescribed | Rees, JA Smith, I and Watson J | 5TH ED., LONDON: CHURCHILL LIVINGSTONE |
| Readings | Martindale: the complete drug reference | Recommended | Pharmaceutical Press | 35TH EDN, LONDON: PHARMACEUTICAL PRESS, 2007. |
| Readings | Physical Chemistry | Recommended | Engel, T and Reid, P 2006 | PEARSON: SAN FRANCISCO |
Graduate capabilities & intended learning outcomes
01. Apply methods of compounding by manufacturing and dispensing a solution product in accordance with the PSA Professional Practice Standard for Compounding.
- Activities:
- Product Labelling And Extemporaneous products: During the semester labelling and documentation for products is assessed. The labelling and documentation must meet the PSA standard, and so students are assessed on these important professional writing skills. At the end of the semester a practical test is given and students must reach the hurdle benchmark by completing the tasks in line with the PSA guidelines. Students are also assessed in the interview, where they can be asked questions on any of the practical tasks they have been given in the semester. They could be asked specifically about a product, a label, or the science of the formulation.
02. Predict and explain the properties of solutions by the calculation and interpretation of thermodynamic parameters and describe how these relate to pharmaceutical solutions.
- Activities:
- Assessed in the exam and during the prac interview. In addition to written calculations, students must be able to explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.
03. Assess the advantages and disadvantages of a wide variety of dosage forms by describing how dosage form can impact on factors such as bioavailability, stability and product handling.
- Activities:
- Assessed in the exam, and during the prac interview. In addition to written calculations, students must be able to explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.
04. Apply pharmacokinetic principles by describing ADME and how this can be affected by dosage form and route of administration.
- Activities:
- Assessed in the final exam and the practical interview.
05. Accurately calculate dosage by completion of calculation hurdle quizzes and test.
- Activities:
- There is a 50 minute calculation test. Preparation is via a series of three LMS quizzes, to sit the calculation test the students must achieve 80% in the 3rd quiz by the test date. The questions in the final test are a selection of questions from these LMS quizzes. Students are allowed to repeat the quizzes to reach the hurdle benchmark until the end of the examination period.
Subject options
Select to view your study options…
Bendigo, 2017, Semester 2, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorDavid Morton
Class requirements
Laboratory ClassWeek: 31 - 43
Seven 3.0 hours laboratory class per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
LectureWeek: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
TutorialWeek: 31 - 43
Two 1.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Pre laboratory and calculation tutorials. On-line quizzes to complete."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 02, 05, 04, 03 | |
| In-class test, Pharmaceutical Calculations | Hurdle requirement: must produce competent documentation and labels, must also achieve 80% for LMS quiz 3. | 10 | 05 |
| Pharmaceutics practical skills | 30 | 04, 03, 02, 01 |
Singapore, 2017, Term L6, Night
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
Laboratory ClassWeek: 45 - 49
One 15.0 hours laboratory class per study period on weekdays at night from week 45 to week 49 and delivered via face-to-face.
"15 hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."
LectureWeek: 45 - 49
One 30.0 hours lecture per study period on weekdays at night from week 45 to week 49 and delivered via face-to-face.
"30 hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online"
TutorialWeek: 45 - 49
One 10.0 hours tutorial per study period on weekdays at night from week 45 to week 49 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 02, 05, 04, 03 | |
| In-class test, Pharmaceutical Calculations | Hurdle requirement: must produce competent documentation and labels, must also achieve 80% for LMS quiz 3. | 10 | 05 |
| Pharmaceutics practical skills | 30 | 04, 03, 02, 01 |
Singapore, 2017, Term L2, Night
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
Laboratory ClassWeek: 12 - 16
One 15.0 hours laboratory class per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."
LectureWeek: 12 - 16
One 30.0 hours lecture per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."
TutorialWeek: 12 - 16
One 10.0 hours tutorial per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 02, 05, 04, 03 | |
| In-class test, Pharmaceutical Calculations | Hurdle requirement: must produce competent documentation and labels, must also achieve 80% for LMS quiz 3. | 10 | 05 |
| Pharmaceutics practical skills | 30 | 04, 03, 02, 01 |
Singapore, 2017, Term L2, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
Laboratory ClassWeek: 12 - 16
One 15.0 hours laboratory class per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."
LectureWeek: 12 - 16
One 30.0 hours lecture per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."
TutorialWeek: 12 - 16
One 10.0 hours tutorial per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 02, 05, 04, 03 | |
| In-class test, Pharmaceutical Calculations | Hurdle requirement: must produce competent documentation and labels, must also achieve 80% for LMS quiz 3. | 10 | 05 |
| Pharmaceutics practical skills | 30 | 04, 03, 02, 01 |
Singapore, 2017, Term L6, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJennifer Selkirk-Bell
Class requirements
Laboratory ClassWeek: 45 - 49
One 15.0 hours laboratory class per study period on weekdays during the day from week 45 to week 49 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."
LectureWeek: 45 - 49
One 30.0 hours lecture per study period on weekdays during the day from week 45 to week 49 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."
TutorialWeek: 45 - 49
One 10.0 hours tutorial per study period on weekdays during the day from week 45 to week 49 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 02, 05, 04, 03 | |
| In-class test, Pharmaceutical Calculations | Hurdle requirement: must produce competent documentation and labels, must also achieve 80% for LMS quiz 3. | 10 | 05 |
| Pharmaceutics practical skills | 30 | 04, 03, 02, 01 |