che2moc med
MEDICINAL AND ORGANIC CHEMISTRY
CHE2MOC
2015
Credit points: 15
Subject outline
This is an elective second year chemistry subject, which is taken in conjunction with CHE2FCA and involves lectures and a laboratory component. This subject will introduce the fundamental concepts of medicinal chemistry, including the definition and classifications of drugs, drug discovery and the role of the medicinal chemistry today. The organic chemistry, reactivity and properties of aromatic compounds will be introduced and the use of infra-red and nuclear magnetic resonance spectroscopy in the identification and characterisation of organic compounds.
SchoolSchool of Molecular Sciences/LIMS
Credit points15
Subject Co-ordinatorIan Potter
Available to Study Abroad StudentsYes
Subject year levelYear Level 2 - UG
Exchange StudentsYes
Subject particulars
Subject rules
Prerequisites Either CHE1BAS or CHE1CHF or CHE1GEN, and CHE1APL
Co-requisites CHE2FCA
Incompatible subjects CHE2MEC
Equivalent subjectsN/A
Special conditionsN/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | Introduction to Medicinal Chemistry, 4rd edition | Prescribed | Patrick, G. | OXFORD UNIVERSITY PRESS, 2009. |
| Readings | Organic Chemistry, 8th edition, 2008 | Prescribed | McMurry, J. | THOMSON-BROOKS/COLE |
Graduate capabilities & intended learning outcomes
01. Explain the fundamental concepts of medicinal chemistry.
- Activities:
- During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. Written assignments will be used to reinforce and assess this ILO.
02. Illustrate how drugs are classified and the methods used in drug discovery.
- Activities:
- During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. The concepts associated with this ILO will be reinforced using online quizzes, administered using LMS. Written assignments will be used to reinforce and assess this ILO.
03. Employ concepts of bonding to explain the properties of aromatic compounds.
- Activities:
- During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. The concepts associated with this ILO will be reinforced using online quizzes administered using LMS. Written assignments will be used to reinforce and assess this ILO.
04. Design synthetic schemes for the preparation of substituted aromatic compounds based on benzene.
- Activities:
- During lectures students will answer short questions individually or as part of small groups thereby reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. The concepts associated with this ILO will be reinforced using online quizzes administered using LMS. Written assignments will be used to reinforce and assess this ILO.
05. Demonstrate practical skills needed to conduct chemical synthesis, chemical analysis and be able to interpret and report the results of spectroscopic measurements.
- Activities:
- Working individually or in small groups students will aquire practical skills required for the manipulation of chemicals for chemical synthesis. Working individually or in small groups students will learn techniques (chemical and instrumental) used in modern chemical analysis. Working individually or in small groups students will learn how to make spectroscopic measurements. Students will develop skills in the preparation of laboratory reports, including the use of correct and appropriate prose and presentation of experimental data and results.
Subject options
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Melbourne, 2015, Semester 1, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorIan Potter
Class requirements
TutorialWeek: 10 - 22
One 1.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
LectureWeek: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Laboratory ClassWeek: 10 - 22
One 3.0 hours laboratory class per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| LMS quiz | 10 | 01, 02, 03, 04 | |
| Three written laboratory reports (300 words each) and three short laboratory reports, | 20 | 03, 05 | |
| Topic assignment: length ~ 500 words. | 10 | 01, 02, 03, 04 | |
| Topic exam for each of the 2 lecture topics during the end of semester exams (2 x 1.5-hr exam) | 60 | 01, 02, 03, 04 |